Human MCRS1 protein fragment (ab92134)
- Product nameHuman MCRS1 protein fragmentSee all MCRS1 proteins and peptides ...
- SourceE. coli
- Amino Acid Sequence
- SequenceMASGTASRSEDEESLAGQKRASSQALGTIPKRRSSSRFIK RKKFDDELV ESSLAKSSTRAKGASGVEPGRCSGSEPSS SEKKKVSKAPSTPVPPSPAP APGLTKRVKKSKQPLQVT KDLGRWKPADDLLLINAVLQTNDLTSVHLGV KFSCRFT LREVQERWYALLYDPVISKLACQAMRQLHPEAIAAIQSKA LF SKAEEQLLSKVGSTSQPTLETFQDLLHRHPDAFYLA RTAKALQAHWQLM KQYYLLEDQTVQPLPKGDQVLNFSD AEDLIDDSKLKDMRDEVLEHELMV ADRRQKREIR
- Amino acids14 to 317
Our Abpromise guarantee covers the use of ab92134 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- Additional NotesProtein Identity confirmed by Mass Spectrometry (MS/MS) (acquired on initial reference batch)
- Concentration information loading...
Preparation and Storage
- Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
- ReconstitutionReconstitute with 61 µl aqua dest.
- 58 kDa microspherule protein
- Cell cycle regulated factor (78 kDa)
- Cell cycle regulated factor p78
- Cell cycle-regulated factor p78
- INO80 complex subunit J
- MCRS 1
- MCRS 2
- Microspherule protein 1
- MSP 58
- FunctionModulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. May be an inhibitor of TERT telomerase activity.
Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
- Tissue specificityDetected in testis, and at lower levels in spleen, thymus, prostate, uterus, small intestine, colon and leukocytes.
- Sequence similaritiesContains 1 FHA domain.
- Developmental stageCell-cycle regulated: levels are highest early in S phase; not detectable in G2.
- Cellular localizationNucleus. Nucleus > nucleolus. In microspherules in the nucleolus.
Human MCRS1 protein fragment images
The image shows an electrophoretic assay performed using an Agilent 5100 ALP. In some images coloured control bands can be seen at 15 kDa (green) and/or 240 kDa (purple). The protein-specific band is blue.
References for Human MCRS1 protein fragment (ab92134)
ab92134 has not yet been referenced specifically in any publications.