Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human

Associated products

Specifications

Our Abpromise guarantee covers the use of ab39815 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2

General Info

  • Alternative names
    • ESOP 1
    • ESOP-1
    • ESOP1
    • LY 96
    • Ly-96
    • LY96
    • LY96_HUMAN
    • Lymphocyte antigen 96
    • md 2
    • MD 2 protein
    • MD2 protein
    • Myeloid differentiation protein 2
    • Protein MD 2
    • Protein MD-2
    • Protein MD2
    see all
  • Function
    Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both MD2 and TLR4, but not TLR4 alone, respond to LPS.
  • Post-translational
    modifications
    N-glycosylated; high-mannose.
  • Cellular localization
    Secreted > extracellular space.
  • Information by UniProt

References

ab39815 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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