The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Monocarboxylate transporter 1
Monocarboxylate transporter isoform 1
Monocarboxylic acid transporter 1
Solute carrier family 16 (monocarboxylic acid transporters) member 1
Solute carrier family 16 member 1
Solute carrier family 16 member 1 (monocarboxylic acid transporter 1)
FunctionProton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate.
Tissue specificityWidely expressed in normal and in cancer cells.
Involvement in diseaseSymptomatic deficiency in lactate transport Familial hyperinsulinemic hypoglycemia 7
Sequence similaritiesBelongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.