Human Monocarboxylic acid transporter 1 peptide (ab97985)

Overview

Description

  • Nature
    Synthetic

Associated products

Specifications

Our Abpromise guarantee covers the use of ab97985 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Purity
    70 - 90% by HPLC.

  • Form
    Liquid
  • Additional notes

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General Info

  • Alternative names
    • FLJ36745
    • HHF7
    • MCT
    • MCT 1
    • MGC44475
    • Monocarboxylate transporter
    • Monocarboxylate transporter 1
    • Monocarboxylate transporter isoform 1
    • Monocarboxylic acid transporter 1
    • MOT1_HUMAN
    • Slc16a1
    • SLC16A1 protein
    • Solute carrier family 16 (monocarboxylic acid transporters) member 1
    • Solute carrier family 16 member 1
    • Solute carrier family 16 member 1 (monocarboxylic acid transporter 1)
    see all
  • Function
    Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate.
  • Tissue specificity
    Widely expressed in normal and in cancer cells.
  • Involvement in disease
    Symptomatic deficiency in lactate transport
    Familial hyperinsulinemic hypoglycemia 7
  • Sequence similarities
    Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt

References

ab97985 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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