Overview

  • Product name
    Human MTA1 peptide

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      PGDVFYMPKE

Associated products

Specifications

Our Abpromise guarantee covers the use of ab45449 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-MTA1 antibody (ab751)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.


General Info

  • Alternative names
    • Metastasis associated 1
    • Metastasis associated gene 1
    • Metastasis associated gene 1 protein
    • Metastasis associated protein
    • Metastasis associated protein MTA 1
    • Metastasis associated protein MTA1
    • Metastasis-associated protein MTA1
    • MTA 1
    • MTA1
    • MTA1_HUMAN
    see all
  • Function
    May be involved in the regulation of gene expression by covalent modification of histone proteins. Isoform Long is a corepressor of estrogen receptor (ER). Isoform Short binds to ER and sequesters it in the cytoplasm and enhances non-genomic responses of ER.
  • Tissue specificity
    Widely expressed. High expression in brain, ovaries, adrenal glands and virgin mammary glands. Higher in tumors than in adjacent normal tissue from the same individual.
  • Sequence similarities
    Contains 1 BAH domain.
    Contains 1 ELM2 domain.
    Contains 1 GATA-type zinc finger.
    Contains 1 SANT domain.
  • Developmental stage
    Highly expressed in metastatic cells.
  • Domain
    Isoform Short contains a Leu-Arg-Ile-Leu-Leu motif (ER binding motif).
  • Cellular localization
    Cytoplasm and Nucleus.
  • Information by UniProt

References

ab45449 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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