Overview

  • Product nameHuman Myosin 18B peptide

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceC-DDVASIMKKYLQK
    • Amino acids2555 to 2567

Specifications

Our Abpromise guarantee covers the use of ab45499 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Info

  • Alternative names
    • BK125H2.1
    • DKFZp434C2422
    • DKFZp779C1668
    • MY18B_HUMAN
    • MYO18B
    • myosin 18B
    • myosin XVIIIB
    • Myosin-XVIIIb
    see all
  • FunctionMay be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth.
  • Tissue specificitySelectively expressed in cardiac and skeletal muscles. Weakly expressed in testis, pancreas, placenta, prostate, lung and thymus.
  • Sequence similaritiesContains 1 IQ domain.
    Contains 1 myosin head-like domain.
  • Developmental stageReaches an expression peak in the third day after induction and remains at similar level during successive myotubule maturation.
  • Cellular localizationCytoplasm. Nucleus. Cytoplasm > myofibril > sarcomere. Punctate pattern in undifferentiated myoblasts. Nuclear, on primary cardiomyocytes and adult muscle. A partial sarcomeric location was found in some cardiomyocytes.
  • Information by UniProt

References for Human Myosin 18B peptide (ab45499)

ab45499 has not yet been referenced specifically in any publications.

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