The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-MYRIP antibody (ab10149)
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Myosin VIIA and Rab interacting protein
Myosin-VIIa- and Rab-interacting protein
Rab effector MyRIP
Slp homolog lacking C2 domains c
Slp homologue lacking C2 domains
Slp homologue lacking C2 domains c
Synaptotagmin like protein homologue lacking C2 domains c
synaptotagmin-like protein lacking C2 domains C
FunctionRab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor proteins MYO5A and MYO7A. May link RAB27A-containing vesicles to actin filaments.
Tissue specificityDetected in brain, skin, heart, adrenal medulla, pancreas, intestine, liver, kidney, muscle and testis.
Cellular localizationCytoplasm. In pre- and post-synaptic areas in photoreceptor cells and in the basal microvilli of retinal pigment epithelium cells. Associated with melanosomes. Colocalizes with actin filaments.