The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Biological activityHuman WASP sequence has a similar peptide sequence surrounding serine 483 and 484.
Phosphorylation regulates the activity of both WASP and N WASP. Dual phosphorylation of WASP on serine 483 and 484 by casein kinases increases its affinity for the ARP2/3 complex. Thus, dual phosphorylation may be important for formation of actin-based structures in various cell types.
Human WASP sequence has a similar peptide sequence surrounding serine 483 and 484.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
FunctionRegulates actin polymerization by stimulating the actin-nucleating activity of the Arp2/3 complex. Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements (HSE) that negatively regulates HSP90 expression.