Nerve growth factor receptor (TNFRSF16) associated protein 1
Nerve growth factor receptor associated protein 1
Nerve growth factor receptor-associated protein 1
NGFR-associated protein 1
Ovarian granulosa cell 13.0 kDa protein HGR74
Ovarian granulosa cell protein
ovarian granulosa cell protein (13kD)
p75NTR associated cell death executor
p75NTR-associated cell death executor
FunctionMay be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.
Tissue specificityFound in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver.
Sequence similaritiesBelongs to the BEX family.
DomainThe nuclear export signal is required for export from the nucleus and the interactions with itself and p75NTR/NGFR.
Post-translational modificationsUbiquitinated. Degraded by the proteasome.
Cellular localizationNucleus. Cytoplasm. Shuttles between the cytoplasm and the nucleus. Associates with replicating mitochondria.