Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human

Associated products

Specifications

Our Abpromise guarantee covers the use of ab39795 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2

General Info

  • Alternative names
    • Baculoviral IAP repeat containing 1
    • Baculoviral IAP repeat-containing protein 1
    • BIRC 1
    • BIRC1
    • BIRC1_HUMAN
    • Birc1a
    • FLJ42520
    • NAIP
    • Naip1
    • Neuronal apoptosis inhibitory protein
    • NLR family apoptosis inhibitory protein
    • NLR family BIR domain containing 1
    • NLRB 1
    • NLRB1
    • Nucleotide binding oligomerization domain leucine rich repeat and BIR domain containing 1
    • Psi neuronal apoptosis inhibitory protein
    • psiNAIP
    • Similar to occludin
    see all
  • Function
    Prevents motor-neuron apoptosis induced by a variety of signals. Possible role in the prevention of spinal muscular atrophy that seems to be caused by inappropriate persistence of motor-neuron apoptosis: mutated or deleted forms of NAIP have been found in individuals with severe spinal muscular atrophy.
  • Tissue specificity
    Expressed in motor neurons, but not in sensory neurons. Found in liver and placenta, and to a lesser extent in spinal cord.
  • Sequence similarities
    Contains 3 BIR repeats.
    Contains 1 NACHT domain.
  • Information by UniProt

References

ab39795 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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