Overview

Description

  • Nature
    Synthetic

Associated products

Specifications

Our Abpromise guarantee covers the use of ab22418 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-NAP1L1 antibody (ab33076)

  • Form
    Liquid
  • Additional notes

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General Info

  • Alternative names
    • FLJ16112
    • hNRP
    • HSP22 like protein interacting protein
    • MGC23410
    • MGC8688
    • NAP 1
    • NAP 1 related protein
    • NAP 1L
    • NAP-1-related protein
    • NAP1
    • NAP1 L1
    • NAP1 related protein
    • NAP1L
    • Nap1l1
    • NAP1L1 protein
    • NP1L1_HUMAN
    • NRP
    • Nucleosome assembly protein 1 like 1
    • Nucleosome assembly protein 1-like 1
    • Nucleosome assembly protein I-related protein
    see all
  • Function
    May be involved in modulating chromatin formation and contribute to regulation of cell proliferation.
  • Tissue specificity
    Ubiquitously expressed.
  • Sequence similarities
    Belongs to the nucleosome assembly protein (NAP) family.
  • Domain
    The acidic domains are probably involved in the interaction with histones.
  • Post-translational
    modifications
    Polyglutamylated by TTLL4, a modification that occurs exclusively on glutamate residues and results in polyglutamate chains on the gamma-carboxyl group. Some residues may also be monoglycylated but not polyglycylated due to the absence of functional TTLL10 in human.
  • Cellular localization
    Nucleus. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt

References

ab22418 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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