Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      C-NSHLLPKKKHQK
    • Amino acids
      177 to 188

Specifications

Our Abpromise guarantee covers the use of ab50441 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Info

  • Alternative names
    • AAC2
    • ARY2_HUMAN
    • Arylamide acetylase 2
    • Arylamide acetylase 2 (N-acetyltransferase 2, isoniazid inactivation)
    • Arylamine N-acetyltransferase 2
    • HGNC:7646
    • N-acetyltransferase 2 (arylamine N-acetyltransferase)
    • N-acetyltransferase type 2
    • NAT-2
    • NAT2
    • PNAT
    • Polymorphic arylamine N-acetyltransferase
    see all
  • Function
    Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens.
  • Sequence similarities
    Belongs to the arylamine N-acetyltransferase family.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt

References

This product has been referenced in:
  • Kim SS  et al. Enhanced expression of two discrete isoforms of matrix metalloproteinase-2 in experimental and human diabetic nephropathy. PLoS One 12:e0171625 (2017). Read more (PubMed: 28178341) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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