Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      C-RNKVDDYIKRYAR
    • Amino acids
      173 to 185

Associated products

Specifications

Our Abpromise guarantee covers the use of ab23264 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-NCE2 antibody (ab15707)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • NCE2
    • NEDD8 carrier protein UBE2F
    • NEDD8 conjugating enzyme
    • NEDD8 conjugating enzyme UBE2F
    • NEDD8 protein ligase UBE2F
    • NEDD8-conjugating enzyme 2
    • NEDD8-conjugating enzyme UBE2F
    • ube2f
    • UBE2F_HUMAN
    • Ubiquitin conjugating enzyme E2F
    • Ubiquitin conjugating enzyme E2F (putative)
    • Ubiquitin-conjugating enzyme E2 F
    see all
  • Function
    Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5.
  • Tissue specificity
    Widely expressed (at protein level).
  • Pathway
    Protein modification; protein neddylation.
  • Sequence similarities
    Belongs to the ubiquitin-conjugating enzyme family. UBE2F subfamily.
  • Information by UniProt

References

ab23264 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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