Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceASSAREHLLFVRR-C
    • Amino acids2 to 14

Specifications

Our Abpromise guarantee covers the use of ab23243 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • C2 and WW domain-containing protein 2
    • E3 ubiquitin protein ligase HECW2
    • E3 ubiquitin-protein ligase HECW2
    • HECT
    • HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
    • Hecw2
    • HECW2_HUMAN
    • KIAA130
    • KIAA1301
    • NEDD4 like E3 ubiquitin protein ligase 2
    • NEDD4 Related E3 Ubiquitin Ligase
    • NEDD4-like E3 ubiquitin-protein ligase 2
    see all
  • FunctionE3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73.
  • Tissue specificityPredominantly expressed in adult brain, lung and heart.
  • PathwayProtein modification; protein ubiquitination.
  • Sequence similaritiesContains 1 C2 domain.
    Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.
    Contains 2 WW domains.
  • Cellular localizationCytoplasm.
  • Information by UniProt

References for Human NEDL2 peptide (ab23243)

ab23243 has not yet been referenced specifically in any publications.

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