Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      ASSAREHLLFVRR-C
    • Amino acids
      2 to 14

Specifications

Our Abpromise guarantee covers the use of ab23243 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • C2 and WW domain-containing protein 2
    • E3 ubiquitin protein ligase HECW2
    • E3 ubiquitin-protein ligase HECW2
    • HECT
    • HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
    • Hecw2
    • HECW2_HUMAN
    • KIAA130
    • KIAA1301
    • NEDD4 like E3 ubiquitin protein ligase 2
    • NEDD4 Related E3 Ubiquitin Ligase
    • NEDD4-like E3 ubiquitin-protein ligase 2
    see all
  • Function
    E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73.
  • Tissue specificity
    Predominantly expressed in adult brain, lung and heart.
  • Pathway
    Protein modification; protein ubiquitination.
  • Sequence similarities
    Contains 1 C2 domain.
    Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.
    Contains 2 WW domains.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt

References

ab23243 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab23243.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up