Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      C-ITMGKEPTLQNHL
    • Amino acids
      633 to 645

Specifications

Our Abpromise guarantee covers the use of ab23299 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • 4932416N14Rik
    • FLJ23495
    • NEK11
    • NEK11_HUMAN
    • NEK11S/L
    • Never in mitosis A-related kinase 11
    • NIMA (never in mitosis gene a) related kinase 11
    • NIMA (never in mitosis gene a)- related kinase 11
    • NIMA related kinase 11L
    • NIMA related kinase 11S
    • NIMA-related kinase 11
    • NimA-related protein kinase 11
    • Serine/threonine-protein kinase Nek11
    see all
  • Function
    Possible role in S-phase checkpoint mechanism.
  • Tissue specificity
    Poorly expressed in cerebellum, trachea, lung, appendix, and uterus.
  • Sequence similarities
    Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
    Contains 1 protein kinase domain.
  • Developmental stage
    Predominantly expressed at S/G2/M phase.
  • Post-translational
    modifications
    Phosphorylated.
  • Cellular localization
    Nucleus. Nucleus > nucleolus. Nuclear during interphase but moves to the polar microtubules during prometaphase and metaphase. Accumulates in the nucleolus in G1/S-arrested cells.
  • Information by UniProt

References for Human NEK11 peptide (ab23299)

ab23299 has not yet been referenced specifically in any publications.

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