Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      C-DKALSGGKRKETLV
    • Amino acids
      529 to 542

Associated products

Specifications

Our Abpromise guarantee covers the use of ab23120 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-NET1 antibody (ab5914)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • ARHG8_HUMAN
    • ARHGEF8
    • GLYT2
    • Guanine nucleotide regulatory protein oncogene
    • MGC114559
    • MGC127767
    • MGC53602
    • mNET1
    • Net1
    • NET1A
    • Neuroepithelial cell transforming gene 1
    • Neuroepithelial cell-transforming gene 1 protein
    • p65 Net1 proto oncogene
    • Proto-oncogene p65 Net1
    • Rho guanine nucleotide exchange factor 8
    • Rho guanine nucleotide exchange factor GEF 8
    see all
  • Function
    Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death.
  • Tissue specificity
    Widely expressed.
  • Sequence similarities
    Contains 1 DH (DBL-homology) domain.
    Contains 1 PH domain.
  • Cellular localization
    Cytoplasm. Nucleus.
  • Information by UniProt

References

ab23120 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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