Overview

Description

  • Nature
    Synthetic

Associated products

Specifications

Our Abpromise guarantee covers the use of ab71176 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Purity
    70 - 90% by HPLC.

  • Form
    Liquid
  • Additional notes

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General Info

  • Alternative names
    • AW490526
    • EIEE27
    • Glutamate [NMDA] receptor subunit epsilon 2
    • Glutamate [NMDA] receptor subunit epsilon-2
    • Glutamate Receptor Ionotropic N Methyl D Aspartate 2B
    • Glutamate Receptor Ionotropic N Methyl D Aspartate subunit 2B
    • Glutamate receptor ionotropic NMDA2B
    • Glutamate receptor subunit epsilon 2
    • Glutamate receptor, ionotropic, NMDA2B (epsilon 2)
    • GRIN 2B
    • GRIN2B
    • hNR 3
    • hNR3
    • MGC142178
    • MGC142180
    • MRD6
    • N methyl D asparate receptor channel subunit epsilon 2
    • N methyl D aspartate receptor subtype 2B
    • N methyl D aspartate receptor subunit 2B
    • N methyl D aspartate receptor subunit 3
    • N-methyl D-aspartate receptor subtype 2B
    • N-methyl-D-aspartate receptor subunit 3
    • NMDA NR2B
    • NMDA R2B
    • NMDAR2B
    • NMDE2
    • NMDE2_HUMAN
    • NME2
    • NR2B
    • NR3
    see all
  • Function
    NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.
  • Tissue specificity
    Primarily found in the fronto-parieto-temporal cortex and hippocampus pyramidal cells, lower expression in the basal ganglia.
  • Sequence similarities
    Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2B/GRIN2B subfamily.
  • Cellular localization
    Cell membrane. Cell junction > synapse > postsynaptic cell membrane.
  • Information by UniProt

References

ab71176 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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