Overview

Description

  • NatureSynthetic

Specifications

Our Abpromise guarantee covers the use of ab71177 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Purity70 - 90% by HPLC.

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General info

  • Alternative names
    • AW490526
    • Glutamate [NMDA] receptor subunit epsilon 2
    • Glutamate [NMDA] receptor subunit epsilon-2
    • Glutamate Receptor Ionotropic N Methyl D Aspartate 2B
    • Glutamate Receptor Ionotropic N Methyl D Aspartate subunit 2B
    • Glutamate receptor ionotropic NMDA2B
    • Glutamate receptor subunit epsilon 2
    • Glutamate receptor, ionotropic, NMDA2B (epsilon 2)
    • GRIN 2B
    • GRIN2B
    • hNR 3
    • hNR3
    • MGC142178
    • MGC142180
    • N methyl D asparate receptor channel subunit epsilon 2
    • N methyl D aspartate receptor subtype 2B
    • N methyl D aspartate receptor subunit 2B
    • N methyl D aspartate receptor subunit 3
    • N-methyl D-aspartate receptor subtype 2B
    • N-methyl-D-aspartate receptor subunit 3
    • NMDA NR2B
    • NMDA R2B
    • NMDAR2B
    • NMDE2
    • NMDE2_HUMAN
    • NME2
    • NR2B
    • NR3
    see all
  • FunctionNMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.
  • Tissue specificityPrimarily found in the fronto-parieto-temporal cortex and hippocampus pyramidal cells, lower expression in the basal ganglia.
  • Sequence similaritiesBelongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2B/GRIN2B subfamily.
  • Cellular localizationCell membrane. Cell junction > synapse > postsynaptic cell membrane.
  • Target information above from: UniProt accession Q13224 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

References for Human NMDAR2B peptide (ab71177)

ab71177 has not yet been referenced specifically in any publications.

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