Overview

Description

  • NatureSynthetic

Associated products

Specifications

Our Abpromise guarantee covers the use of ab34172 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • FormLiquid
  • Additional notes

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General Info

  • Alternative names
    • Azoreductase
    • Cytochrome b 5 reductase
    • DHQU
    • DIA 4
    • DIA4
    • Diaphorase (NADH/NADPH)
    • Diaphorase (NADH/NADPH) (cytochrome b 5 reductase)
    • Diaphorase 4
    • Dioxin inducible 1
    • DT diaphorase
    • DT-diaphorase
    • DTD
    • Menadione reductase
    • NAD(P)H dehydrogenase [quinone] 1
    • NAD(P)H dehydrogenase quinone 1
    • NAD(P)H menadione oxidoreductase 1 dioxin inducible
    • NAD(P)H: menadione oxidoreductase 1 dioxin inducible 1
    • NAD(P)H:menadione oxidoreductase 1
    • NAD(P)H:Quinone acceptor oxidoreductase type 1
    • NAD(P)H:quinone oxidoreductase 1
    • NAD(P)H:quinone oxireductase
    • NMOR 1
    • NMOR I
    • NMOR1
    • NMORI
    • NQO 1
    • NQO1
    • NQO1_HUMAN
    • Phylloquinone reductase
    • QR 1
    • QR1
    • Quinone reductase 1
    see all
  • FunctionThe enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.
  • Sequence similaritiesBelongs to the NAD(P)H dehydrogenase (quinone) family.
  • Cellular localizationCytoplasm.
  • Information by UniProt

References for Human NQO1 peptide (ab34172)

ab34172 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"