Overview

Description

  • NatureSynthetic

Associated products

Specifications

Our Abpromise guarantee covers the use of ab98247 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Purity70 - 90% by HPLC.

  • FormLiquid
  • Additional notes

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General Info

  • Alternative names
    • Antiapoptotic protein GW112
    • bA209J19.1
    • G-CSF-stimulated clone 1 protein
    • GC1
    • GW112
    • hGC 1
    • hGC-1
    • hOLfD
    • KIAA4294
    • olfactomedin 4
    • Olfactomedin-4
    • OlfD
    • OLFM4
    • OLFM4_HUMAN
    • OLM4
    • UNQ362
    see all
  • FunctionAn antiapoptotic factor that promotes tumor growth. Promotes proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. Facilitates cell adhesion.
  • Tissue specificityExpressed during myeloid lineage development. Strongly expressed in the prostate, small intestine and colon and moderately expressed in the bone marrow and stomach. Highly expressed in pancreatic cancer tissues and shows an elevated expression level during the early S phase of the cell cycle. Also expressed at high levels in stomach cancer and colon cancer tissues.
  • Sequence similaritiesContains 1 olfactomedin-like domain.
  • DomainThe olfactomedin-like domain is involved in the interaction with cadherin.
  • Post-translational
    modifications
    N-glycosylated.
  • Cellular localizationSecreted > extracellular space. According to PubMed:15059901, found in mitochondrion and nucleus.
  • Information by UniProt

References for Human OLFM4 peptide (ab98247)

ab98247 has not yet been referenced specifically in any publications.

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