The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-P2X2 antibody (ab48864)
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
P2X purinoceptor 2
P2X Receptor subunit 2
Purinergic receptor P2X ligand gated ion channel 2
Purinergic receptor P2X2 isoform A
Purinergic receptor P2X2 isoform B
Purinergic receptor P2X2 isoform C
Purinergic receptor P2X2 isoform D
Purinergic receptor P2X2 isoform H
Purinergic receptor P2X2 isoform I
FunctionIon channel gated by extracellular ATP involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle.
Involvement in diseaseDeafness, autosomal dominant, 41
Sequence similaritiesBelongs to the P2X receptor family.
Cellular localizationCell membrane. Localizes to the apical membranes of hair cells in the organ of Corti.