Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequencePKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTEL
    • Amino acids181 to 230

Associated products

Specifications

Our Abpromise guarantee covers the use of ab95915 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-P2X2 antibody (ab48864)

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: dH2O

General Info

  • Alternative names
    • ATP receptor
    • MGC129601
    • P2RX 2
    • P2RX2
    • P2RX2_HUMAN
    • P2X purinoceptor 2
    • P2X Receptor subunit 2
    • P2X2
    • P2X2a
    • Purinergic receptor
    • Purinergic receptor P2X ligand gated ion channel 2
    • Purinergic receptor P2X2 isoform A
    • Purinergic receptor P2X2 isoform B
    • Purinergic receptor P2X2 isoform C
    • Purinergic receptor P2X2 isoform D
    • Purinergic receptor P2X2 isoform H
    • Purinergic receptor P2X2 isoform I
    see all
  • FunctionIon channel gated by extracellular ATP involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle.
  • Involvement in diseaseDeafness, autosomal dominant, 41
  • Sequence similaritiesBelongs to the P2X receptor family.
  • Cellular localizationCell membrane. Localizes to the apical membranes of hair cells in the organ of Corti.
  • Information by UniProt

References for Human P2X2 peptide (ab95915)

ab95915 has not yet been referenced specifically in any publications.

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