Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      DLEKNYPTPRTSR-C
    • Amino acids
      2 to 14

Associated products

Specifications

Our Abpromise guarantee covers the use of ab22941 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-PAX5 antibody (ab2935)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • B cell lineage specific activator
    • B cell lineage specific activator protein
    • B cell specific activator protein
    • B cell specific transcription factor
    • B-cell-specific transcription factor
    • BSAP
    • EBB-1
    • KLP
    • Paired box 5
    • Paired box gene 5
    • Paired box gene 5 (B cell lineage specific activator protein)
    • Paired box gene 5 (B cell lineage specific activator)
    • Paired box homeotic gene 5
    • Paired box protein Pax 5
    • Paired box protein Pax-5
    • Paired domain gene 5
    • PAX 5
    • PAX5
    • PAX5_HUMAN
    • Transcription factor PAX 5
    see all
  • Function
    May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene.
  • Involvement in disease
    A chromosomal aberration involving PAX5 is a cause of acute lymphoblastic leukemia. Translocation t(9;18)(p13;q11.2) with ZNF521. Translocation t(9;3)(p13;p14.1) with FOXP1. Translocation t(9;12)(p13;p13) with ETV6.
    Leukemia, acute lymphoblastic, 3
  • Sequence similarities
    Contains 1 paired domain.
  • Developmental stage
    Expressed at early B-cell differentiation, in the developing CNS and in adult testis.
  • Post-translational
    modifications
    O-glycosylated.
  • Cellular localization
    Nucleus.
  • Information by UniProt

References

ab22941 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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