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Amino Acid Sequence
Sequence This sequence is highly conserved in rat and mouse paxillin and is found in all three isoforms, alpha, beta and gamma. Specifications
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Concentration information loading... Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.05% Sodium Azide
Paired box protein Pax 1
Function Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).
Sequence similarities Belongs to the paxillin family. Contains 4 LIM zinc-binding domains.
Post-translational modifications Phosphorylated on tyrosine residues during integrin-mediated cell adhesion, embryonic development, fibroblast transformation and following stimulation of cells by mitogens.
Cellular localization Cytoplasm > cytoskeleton. Cell junction > focal adhesion.
Information by UniProt
References for Human Paxillin peptide (ab42723)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"