The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions. - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer. - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent. - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised. - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Information available upon request.
Pancreas specific protein disulfide isomerase
Pancreas-specific protein disulfide isomerase
Pancreatic protein disulfide isomerase
Protein disulfide isomerase
Protein disulfide isomerase A2
Protein disulfide isomerase associated 2
Protein disulfide isomerase family A member 2
Protein disulfide isomerase pancreatic
Protein disulfide-isomerase A2
Rho GDP dissociation inhibitor gamma
FunctionActs as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins.
Tissue specificityHighly expressed in pancreas (at protein level).
Sequence similaritiesBelongs to the protein disulfide isomerase family. Contains 2 thioredoxin domains.
Post-translational modificationsThe disulfide-linked homodimer exhibits an enhanced chaperone activity. Glycosylated.