Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      DIDLSDVELDDLGKDEL
    • Amino acids
      476 to 492

Associated products

Specifications

Our Abpromise guarantee covers the use of ab39768 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Neutralising

    Blocking - Blocking peptide for Anti-PDIA6 antibody (ab11432)

  • Purity
    > 90 % SDS-PAGE.

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Double distilled water.

General Info

  • Alternative names
    • Endoplasmic reticulum protein 5
    • ER protein 5
    • ERp5
    • P5
    • Pdia6
    • PDIA6_HUMAN
    • Protein disulfide isomerase A6
    • Protein disulfide isomerase associated 6
    • Protein disulfide isomerase family A member 6
    • Protein disulfide isomerase P5
    • Protein disulfide isomerase related protein
    • Protein disulfide-isomerase A6
    • Thioredoxin domain containing 7 (protein disulfide isomerase)
    • Thioredoxin domain containing protein 7
    • Thioredoxin domain-containing protein 7
    • TXNDC7
    see all
  • Function
    May function as a chaperone that inhibits aggregation of misfolded proteins. Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin.
  • Tissue specificity
    Expressed in platelets (at protein level).
  • Sequence similarities
    Belongs to the protein disulfide isomerase family.
    Contains 2 thioredoxin domains.
  • Cellular localization
    Endoplasmic reticulum lumen. Cell membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt

References

ab39768 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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