Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      GGLEKKKYERGSA
    • Amino acids
      2 to 14

Associated products

Specifications

Our Abpromise guarantee covers the use of ab45502 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-Pescadillo antibody (ab19036)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

General Info

  • Alternative names
    • FLJ43790
    • Homo sapiens pescadillo mRNA complete cds
    • PES
    • PES 1
    • pes1
    • PESC_HUMAN
    • Pescadillo (zebrafish) homolog 1 containing BRCT domain
    • Pescadillo homolog
    • Pescadillo homolog 1
    • Pescadillo homolog 1 containing BRCT domain (zebrafish)
    • Pescadillo ribosomal biogenesis factor 1
    see all
  • Function
    Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
  • Tissue specificity
    Significant levels are detected in a variety of cancer cell lines, including glioblastoma, breast carcinoma, colon carcinoma and cervical carcinoma cells. Levels are abnormally elevated in malignant tumors of astrocytic origin.
  • Sequence similarities
    Belongs to the pescadillo family.
    Contains 1 BRCT domain.
  • Post-translational
    modifications
    Sumoylated.
  • Cellular localization
    Nucleus > nucleolus. Nucleus > nucleoplasm. Chromosome. Appears to localize to the periphery of metaphase chromosomes during mitosis and to the prenucleolar bodies that form in mitotic cells prior to the actual nucleoli.
  • Information by UniProt

References

ab45502 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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