Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceGGLSGCPERGLSD
    • Amino acids308 to 320

Specifications

Our Abpromise guarantee covers the use of ab22923 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • ART1
    • FLJ17158
    • FLJ97586
    • MGC22455
    • Pan hematopoietic expression
    • PHEMX
    • PHMX
    • Tetraspanin
    • tetraspanin 32
    • tetraspanin32
    • TSPAN32
    • TSSC6
    • Tumor suppressing STF cDNA 6
    • Tumor suppressing subchromosomal transferable fragment cDNA 6
    • Tumor suppressing subtransferable candidate 6
    see all
  • RelevancePHEMX belongs to the conserved tetraspanin family of integral membrane proteins, which are thought to form multiprotein networks in the cell membrane in association with multiple protein partners. Tetraspanins have functional roles in cell motility, membrane fusion, proliferation, and adaptive immunity. This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. PHEMX may play a role in malignancies and disease that involve this region as well as hematopoietic cell function. There are 5 isoforms produced by alternative splicing.
  • Cellular localizationMembrane; Multi-pass membrane protein

References for Human PHEMX peptide (ab22923)

ab22923 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"