Overview

  • Product nameHuman Pokemon peptide

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceC-GAATDGNFTAGLA
    • Amino acids572 to 584

Specifications

Our Abpromise guarantee covers the use of ab23084 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • Factor binding IST protein 1
    • Factor that binds to inducer of short transcripts protein 1
    • FBI 1
    • FBI-1
    • FBI1
    • HIV 1 1st binding protein 1
    • HIV-1 1st-binding protein 1
    • Leukemia/lymphoma related factor
    • Leukemia/lymphoma-related factor
    • LRF
    • POK erythroid myeloid ontogenic factor
    • Pokemon
    • POZ and Krueppel erythroid myeloid ontogenic factor
    • TIP21
    • TTF I interacting peptide 21
    • TTF-I-interacting peptide 21
    • ZBT7A_HUMAN
    • ZBTB7
    • ZBTB7A
    • Zinc finger and BTB domain containing protein 7A
    • Zinc finger and BTB domain-containing protein 7A
    • Zinc finger protein 857A
    see all
  • FunctionPlays a key role in the instruction of early lymphoid progenitors to develop into B lineage by repressing T-cell instructive Notch signals (By similarity). Specifically represses the transcription of the CDKN2A gene. Efficiently abrogates E2F1-dependent CDKN2A transactivation/de-repression. Binds to the consensus sequence 5'-[GA][CA]GACCCCCCCCC-3'.
  • Tissue specificityWidely expressed. In normal thymus, expressed in medullary epithelial cells and Hassle's corpuscles (at protein level). In tonsil, expressed in squamous epithelium and germinal center lymphocytes (at protein level). Up-regulated in a subset of lymphomas, as well as in a subset of breast, lung, colon, prostate and bladder carcinomas (at protein level).
  • Sequence similaritiesContains 1 BTB (POZ) domain.
    Contains 4 C2H2-type zinc fingers.
  • Cellular localizationNucleus.
  • Information by UniProt

References for Human Pokemon peptide (ab23084)

ab23084 has not yet been referenced specifically in any publications.

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