Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      C-QRLTPQVAASGGQS
    • Amino acids
      484 to 497

Associated products

Specifications

Our Abpromise guarantee covers the use of ab22848 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-PPP2R5B antibody (ab1366)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • 2A5B_HUMAN
    • B56B
    • Beta isoform of regulatory subunit B56 protein phosphatase 2A
    • FLJ35411
    • PP2A B subunit B' beta isoform
    • PP2A B subunit B56 beta isoform
    • PP2A B subunit isoform B' beta
    • PP2A B subunit isoform B''-beta
    • PP2A B subunit isoform B56-beta
    • PP2A B subunit isoform PR61-beta
    • PP2A B subunit isoform R5-beta
    • PP2A B subunit PR61 beta isoform
    • PP2A B subunit R5 beta isoform
    • PPP2R5B
    • PR 61B
    • PR61B
    • Protein phosphatase 2 regulatory subunit B (B56) beta
    • Protein phosphatase 2 regulatory subunit B (B56) beta isoform
    • Protein phosphatase 2 regulatory subunit B' beta
    • Protein phosphatase 2 regulatory subunit B' beta isoform
    • Serine/threonine protein phosphatase 2A 56 kDa regulatory subunit beta isoform
    • Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform
    see all
  • Function
    The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The phosphorylated form mediates the interaction between AKT1 and PP2A phosphatase leading to dephosphorylation of AKT1 on the 'Thr-308' and 'Ser-373' residues.
  • Tissue specificity
    Highest expression in brain.
  • Sequence similarities
    Belongs to the phosphatase 2A regulatory subunit B56 family.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt

References

ab22848 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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