The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-PRAM1 antibody (ab805)
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
PML RARA regulated adaptor molecule 1
PML RARA target gene encoding an Adaptor Molecule 1
PML-RARA-regulated adapter molecule 1
FunctionMay be involved in myeloid differentiation. May be involved in integrin signaling in neutrophils. Binds to PtdIns(4)P.
Tissue specificityExpressed in peripheral blood leukocytes and bone marrow. Expressed in monocytes, and to a lesser extent in granulocytes and lymphocytes. Not expressed in non hematopoietic tissues except in lung.
Sequence similaritiesContains 1 SH3 domain.
DomainThe SH3 domain binds to PtdIns(4)P.
Post-translational modificationsMay be phosphorylated on tyrosines.