Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceDFCDPLENQPLPLGR
    • Amino acids656 to 670

Associated products

Specifications

Our Abpromise guarantee covers the use of ab22785 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-PRAM1 antibody (ab805)

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • PML RAR
    • PML RARA regulated adaptor molecule 1
    • PML RARA target gene encoding an Adaptor Molecule 1
    • PML-RARA-regulated adapter molecule 1
    • PRAM
    • PRAM 1
    • PRAM-1
    • PRAM_HUMAN
    • PRAM1
    see all
  • FunctionMay be involved in myeloid differentiation. May be involved in integrin signaling in neutrophils. Binds to PtdIns(4)P.
  • Tissue specificityExpressed in peripheral blood leukocytes and bone marrow. Expressed in monocytes, and to a lesser extent in granulocytes and lymphocytes. Not expressed in non hematopoietic tissues except in lung.
  • Sequence similaritiesContains 1 SH3 domain.
  • DomainThe SH3 domain binds to PtdIns(4)P.
  • Post-translational
    modifications
    May be phosphorylated on tyrosines.
  • Information by UniProt

References for Human PRAM1 peptide (ab22785)

ab22785 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"