Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • Sequence(c)SDRSALLKSKLRAL
    • Amino acids80 to 93

Specifications

Our Abpromise guarantee covers the use of ab27128 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.

General Info

  • Alternative names
    • ANF
    • ANF_HUMAN
    • ANP
    • ATFB6
    • Atrial natriuretic factor
    • Atrial natriuretic peptide
    • Atriopeptin
    • ATRST2
    • Cardiodilatin
    • Cardiodilatin-related peptide
    • Cardionatrin
    • CDD
    • CDD ANF
    • CDD-ANF
    • CDP
    • Natriuretic peptide A
    • Natriuretic peptide precursor A
    • Natriuretic peptides A
    • NPPA
    • PND
    • Prepronatriodilatin
    • Pronatriodilatin
    see all
  • FunctionHormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
  • Involvement in diseaseAtrial standstill 2
    Atrial fibrillation, familial, 6
  • Sequence similaritiesBelongs to the natriuretic peptide family.
  • Post-translational
    modifications
    Cleaved by CORIN upon secretion to produce the functional hormone.
    Atrial natriuretic factor: Cleaved by MME. The cleavage initiates degradation of the factor and thereby regulate its activity.
  • Cellular localizationSecreted.
  • Information by UniProt

References for Human proANP peptide (ab27128)

ab27128 has not yet been referenced specifically in any publications.

Product Wall

Unfortunately we are unable to supply a biotinylated form of the peptide. I hope you will be satisfied with ab27128, please let me know if you need more information,

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"