Human proANP peptide (ab42339)
Key features and details
- Purity: > 95% SDS-PAGE
- Suitable for: Blocking
Description
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Product name
Human proANP peptide
See all proANP proteins and peptides -
Purity
> 95 % SDS-PAGE. -
Accession
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Animal free
No -
Nature
Synthetic -
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Species
Human -
Sequence
EVVPPQVLSEPNEEAGAALSPLPEVPPWTGEVSPAQR -
Amino acids
56 to 92
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Specifications
Our Abpromise guarantee covers the use of ab42339 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Blocking
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Form
Lyophilized -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.
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ReconstitutionResuspend in 1ml 0.1% acetic acid for required concentration
General Info
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Alternative names
- ANF
- ANF_HUMAN
- ANP
see all -
Function
Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3. -
Involvement in disease
Atrial standstill 2
Atrial fibrillation, familial, 6 -
Sequence similarities
Belongs to the natriuretic peptide family. -
Post-translational
modificationsCleaved by CORIN upon secretion to produce the functional hormone.
Atrial natriuretic factor: Cleaved by MME. The cleavage initiates degradation of the factor and thereby regulate its activity. -
Cellular localization
Secreted. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab42339 has not yet been referenced specifically in any publications.