Overview

Description

  • NatureSynthetic

Specifications

Our Abpromise guarantee covers the use of ab28492 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-Prohibitin antibody - Mitochondrial Marker (ab28172)

  • FormLiquid
  • Additional notes

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General Info

  • Alternative names
    • Epididymis luminal protein 215
    • Epididymis secretory sperm binding protein Li 54e
    • HEL 215
    • HEL S 54e
    • PHB
    • PHB_HUMAN
    • PHB1
    • Prohibitin
    see all
  • FunctionProhibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging.
  • Tissue specificityWidely expressed in different tissues.
  • Sequence similaritiesBelongs to the prohibitin family.
  • Developmental stageLevels of expression in fibroblasts decrease heterogeneously during cellular aging.
  • Cellular localizationMitochondrion inner membrane.
  • Information by UniProt

References for Human Prohibitin peptide (ab28492)

ab28492 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"