Human Proteasome 20S beta 6 peptide (ab4947)

Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • AccessionP28072
    • SpeciesHuman
    • SequenceAn 18 amino acid synthetic peptide whose sequence is derived from human proteasome 20S beta 6 and amino acid residues 74-91 from frog protein. The sequence of this peptide is (amino to carboxy terminus): C(41)RSGSAADTQAV/IADAVTY(58).
    • Amino acids74 to 90

Associated products

Specifications

Our Abpromise guarantee covers the use of ab4947 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • FormLiquid
  • Additional notes


    This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and human proteasome 20S beta 6, catalog ab3331. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~ 70-fold) for competitive inhibition of antibody-protein binding reactions.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

General Info

  • Alternative names
    • DELTA
    • LMPY
    • Macropain delta chain
    • MGC5169
    • Multicatalytic endopeptidase complex delta chain
    • Proteasome (prosome macropain) subunit beta type 6
    • Proteasome beta 6 subunit
    • Proteasome catalytic subunit 1
    • Proteasome delta chain
    • Proteasome subunit beta 6
    • Proteasome subunit beta type 6
    • Proteasome subunit beta type-6
    • Proteasome subunit delta
    • Proteasome subunit Y
    • PSB6_HUMAN
    • PSMB6
    • PSY large multifunctional protease Y
    • Y
    see all
  • FunctionThe proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the peptidyl glutamyl-like activity. May catalyze basal processing of intracellular antigens.
  • Sequence similaritiesBelongs to the peptidase T1B family.
  • Cellular localizationCytoplasm. Nucleus.
  • Information by UniProt

References for Human Proteasome 20S beta 6 peptide (ab4947)

ab4947 has not yet been referenced specifically in any publications.

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