Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceDGIVPDIAVGTKR-C
    • Amino acids2 to 14

Associated products

Specifications

Our Abpromise guarantee covers the use of ab23105 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-PTBP1 antibody (ab5642)

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • 57 kDa RNA binding protein PPTB 1
    • 57 kDa RNA-binding protein PPTB-1
    • Heterogeneous nuclear ribonucleoprotein I
    • Heterogeneous Nuclear Ribonucleoprotein Polypeptide I
    • hnRNP I
    • HNRNP-I
    • HNRNPI
    • HNRPI
    • MGC10830
    • MGC8461
    • Polypyrimidine tract binding protein
    • Polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I)
    • Polypyrimidine Tract Binding Protein 1
    • Polypyrimidine tract-binding protein 1
    • pPTB
    • PTB
    • PTB 1
    • PTB 2
    • PTB 3
    • PTB 4
    • PTB T
    • PTB1
    • PTB2
    • PTB3
    • PTB4
    • PTBP 1
    • PTBP1
    • PTBP1_HUMAN
    • PTBT
    • RNA Binding Protein
    see all
  • FunctionPlays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA.
  • Sequence similaritiesContains 4 RRM (RNA recognition motif) domains.
  • Cellular localizationNucleus.
  • Information by UniProt

References for Human PTBP1 peptide (ab23105)

ab23105 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"