Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      PLPRGHRAPEMEPN amino acids 180 to 193 of human PUMA-a (1)
    • Amino acids
      180 to 193

Associated products

Specifications

Our Abpromise guarantee covers the use of ab9644 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-PUMA antibody (ab9643)

  • Form
    Liquid
  • Additional notes

    The peptide is used for blocking the activity of anti-PUMA antibody (ab9643). Incubate the peptide with equal volume of antibody for 30 min at 37°C.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    PBS with 0.1% BSA 0.02% sodium azide pH7.2

General Info

  • Alternative names
    • BBC 3
    • Bbc3
    • BBC3_HUMAN
    • BCL 2 binding component 3
    • Bcl-2-binding component 3
    • BCL2 binding component 3
    • JFY 1
    • JFY-1
    • JFY1
    • p53 up regulated modulator of apoptosis
    • p53 up-regulated modulator of apoptosis
    • p53 Upregulated Modulator of Apoptosis
    • PUMA alpha
    • PUMA/JFY1
    see all
  • Function
    Essential mediator of p53-dependent and p53-independent apoptosis.
  • Tissue specificity
    Ubiquitously expressed.
  • Sequence similarities
    Belongs to the Bcl-2 family.
  • Cellular localization
    Mitochondrion. Localized to the mitochondria in order to induce cytochrome c release.
  • Information by UniProt

References

ab9644 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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