Overview

  • Product name
    Human Rabenosyn 5 peptide

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      C-ELKHTLAKQKGGTD
    • Amino acids
      771 to 784

Associated products

Specifications

Our Abpromise guarantee covers the use of ab45507 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-Rabenosyn 5 antibody (ab21196)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

General Info

  • Alternative names
    • 110 kDa protein
    • FYVE finger containing Rab5 effector protein Rabenosyn 5
    • FYVE finger-containing Rab5 effector protein rabenosyn-5
    • Rabenosyn-5
    • RBNS5_HUMAN
    • Zfyve20
    • zinc finger FYVE domain containing 20
    • Zinc finger FYVE domain-containing protein 20
    see all
  • Function
    Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3).
  • Sequence similarities
    Contains 1 C2H2-type zinc finger.
    Contains 1 FYVE-type zinc finger.
    Contains 1 UIM (ubiquitin-interacting motif) repeat.
  • Cellular localization
    Cell membrane. Early endosome membrane.
  • Information by UniProt

Images

  • Human Rabenosyn 5 peptide (ab45507) at 0.3 µg/ml + A431 whole cell lysate (ab7909)

References

ab45507 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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