Overview

Description

  • NatureSynthetic

Specifications

Our Abpromise guarantee covers the use of ab71608 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Purity70 - 90% by HPLC.

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General info

  • Alternative names
    • RAB guanine nucleotide exchange factor (GEF) 1
    • Rab5 GDP/GTP exchange factor
    • Rab5ef
    • Rabaptin 5 associated exchange factor for Rab5
    • Rabaptin-5-associated exchange factor for Rab5
    • Rabex 5
    • Rabex-5
    • RABGEF 1
    • RABGEF1
    • RABX 5
    • RABX5
    • RABX5_HUMAN
    • RAP1
    • Rin 2
    • Rin2
    see all
  • FunctionRab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase.
  • Sequence similaritiesContains 1 A20-type zinc finger.
    Contains 1 VPS9 domain.
  • Post-translational
    modifications
    Monoubiquitinated.
  • Cellular localizationCytoplasm. Early endosome. Recycling endosome.
  • Target information above from: UniProt accession Q9UJ41 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

References for Human Rabex5 peptide (ab71608)

ab71608 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"