Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequencePQPTRQQKRACSLL
    • Amino acids179 to 192

Associated products

Specifications

Our Abpromise guarantee covers the use of ab22892 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-RAC2 antibody (ab2244)

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • EN 7
    • EN-7
    • EN7
    • GX
    • HSPC 022
    • HSPC022
    • p21 Rac 2
    • p21 Rac2
    • p21-Rac2
    • p21Rac2
    • RAC 2
    • Rac2
    • RAC2_HUMAN
    • Ras related C3 botulinum toxin substrate 2
    • Ras related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2
    • Ras related C3 botulinum toxin substrate 3
    • Ras related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac2)
    • Ras-related C3 botulinum toxin substrate 2
    • Rho family small GTP binding protein Rac 2
    • Rho family small GTP binding protein Rac2
    • Small G protein
    see all
  • FunctionPlasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase.
  • Tissue specificityHematopoietic specific.
  • Involvement in diseaseDefects in RAC2 are the cause of neutrophil immunodeficiency syndrome (NEUID) [MIM:608203].
  • Sequence similaritiesBelongs to the small GTPase superfamily. Rho family.
  • Cellular localizationCytoplasm. Membrane-associated when activated.
  • Information by UniProt

References for Human RAC2 peptide (ab22892)

ab22892 has not yet been referenced specifically in any publications.

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