Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      C-ARVKPLHPNATST
    • Amino acids
      340 to 352

Associated products

Specifications

Our Abpromise guarantee covers the use of ab23286 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-RAD51AP1 antibody (ab15957)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • 2510006L10Rik
    • MGC156698
    • OTTMUSP00000028651
    • PIR51
    • R51A1_HUMAN
    • RAB22
    • RAD51 associated protein 1
    • RAD51 interacting protein
    • RAD51-associated protein 1
    • RAD51-interacting protein
    • Rad51ap1
    see all
  • Function
    May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Functionally cooperates with PALB2 in promoting of D-loop formation by RAD51. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA.
  • Tissue specificity
    Highly expressed in testis and thymus. Lower levels in colon and small intestine. Little or no expression in spleen, prostate, ovary and peripheral blood leukocytes.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization
    Nucleus. Colocalizes with RAD51 to multiple nuclear foci.
  • Information by UniProt

References

ab23286 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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