Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceCAGDRLTGIPSHILNSSPSD Amino acids 99 to 117 of human RAIDD (1,2)
    • Amino acids99 to 117

Specifications

Our Abpromise guarantee covers the use of ab8460 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-RAIDD antibody (ab8426)

    Western blot

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    PBS with 0.1% BSA 0.02% sodium azide pH7.2

General Info

  • Alternative names
    • CASP2 and RIPK1 domain containing adaptor with death domain
    • Caspase and RIP adapter with death domain
    • Caspase and RIP adaptor with death domain
    • Cradd
    • CRADD_HUMAN
    • Death adaptor molecule RAIDD
    • Death domain containing protein CRADD
    • Death domain-containing protein CRADD
    • MGC9163
    • RIP associated ICH1/CED3 homologous protein with death domain
    • RIP associated protein with a death domain
    • RIP-associated protein with a death domain
    see all
  • FunctionApoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex.
  • Tissue specificityConstitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney.
  • Sequence similaritiesContains 1 CARD domain.
    Contains 1 death domain.
  • DomainContains a death domain involved in the binding of RIP protein.
    The CARD domain mediates the interaction with caspase-2.
  • Information by UniProt

References for Human RAIDD peptide (ab8460)

ab8460 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab8460.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"