- First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions. - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer. - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent. - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised. - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Information available upon request.
G protein coupled receptor GPCR135
G protein coupled receptor SALPR
G protein-coupled receptor SALPR
G-protein coupled receptor GPCR135
Gprotein coupled receptor SALPR
Relaxin 3 receptor 1
Relaxin 3 receptor1
Relaxin 3/INSL7 receptor 1
Relaxin 3/INSL7 receptor1
Relaxin family peptide receptor 3
Relaxin family peptide receptor3
Relaxin-3 receptor 1
Relaxin/insulin like family peptide receptor 3
Relaxin3 receptor 1
RLN3 receptor 1
somatostatin and angiotensin like peptide receptor
Somatostatin- and angiotensin-like peptide receptor
FunctionReceptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation.
Tissue specificityExpressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.