Human Retinoic Acid Receptor gamma 2 peptide (ab39774)

Overview

  • Product name
    Human Retinoic Acid Receptor gamma 2 peptide

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      RRLYGAAGPGAGLLRR
    • Amino acids
      13 to 28

Associated products

Specifications

Our Abpromise guarantee covers the use of ab39774 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Neutralising

    Blocking - Blocking peptide for Anti-Retinoic Acid Receptor gamma 2 antibody (ab5905)

  • Purity
    > 90 % SDS-PAGE.

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Info

  • Alternative names
    • NR1B3
    • Nuclear receptor subfamily 1 group B member 3
    • RAR gamma
    • RAR gamma isoform 2
    • RAR gamma2
    • RAR-gamma
    • RARC
    • Rarg
    • RARG_HUMAN
    • retinoic acid nuclear receptor gamma variant 1
    • retinoic acid nuclear receptor gamma variant 2
    • Retinoic acid receptor gamma
    see all
  • Function
    Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function.
  • Sequence similarities
    Belongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • Domain
    Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt

References

ab39774 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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