Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      TDALLPAAPQPLEK-C
    • Amino acids
      2 to 15

Specifications

Our Abpromise guarantee covers the use of ab23148 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • 76 kDa RhoB effector protein
    • D7Ertd784e
    • GTP Rho binding protein 2
    • GTP-Rho-binding protein 2
    • p76RBE
    • Rho GTPase binding protein 2
    • RhoB effector
    • RhoBP
    • Rhophilin
    • Rhophilin 2
    • Rhophilin like protein
    • Rhophilin like Rho GTPase binding protein
    • Rhophilin Rho GTPase binding protein 2
    • Rhophilin-2
    • Rhophilin2
    • RHPN 2
    • RHPN2
    • RHPN2_HUMAN
    see all
  • Function
    Binds specifically to GTP-Rho. May function in a Rho pathway to limit stress fiber formation and/or increase the turnover of F-actin structures in the absence of high levels of RhoA activity.
  • Tissue specificity
    Widely expressed. Highly expressed in prostate, trachea, stomach, colon, thyroid and pancreas. Expressed at lower level in brain, spinal cord, kidney, placenta and liver.
  • Sequence similarities
    Belongs to the RHPN family.
    Contains 1 BRO1 domain.
    Contains 1 PDZ (DHR) domain.
    Contains 1 REM (Hr1) repeat.
  • Cellular localization
    Cytoplasm > perinuclear region.
  • Information by UniProt

References for Human Rhophilin 2 peptide (ab23148)

ab23148 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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