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Amino Acid Sequence
Amino acids 369 to 381 Specifications
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-RNF13 antibody (
Concentration information loading... Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
E3 ubiquitin-protein ligase RNF13
Function E3 ubiquitin-protein ligase that may play a role in controlling cell proliferation.
Tissue specificity Widely expressed (at protein level). In normal pancreas, expressed in islets, but not in ducts, nor in acini (at protein level).
Pathway Protein modification; protein ubiquitination.
Sequence similarities Contains 1 PA (protease associated) domain. Contains 1 RING-type zinc finger.
Domain The RING-type zinc finger domain is required for E3 ligase activity.
Post-translational modifications Auto-ubiquitinated.
Cellular localization Endoplasmic reticulum membrane. Golgi apparatus membrane. Late endosome membrane. Lysosome membrane. Nucleus inner membrane. Under certain conditions, relocalizes to recycling endosomes and to the inner nuclear membrane.
Information by UniProt
References for Human RNF13 peptide (ab23020)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"