Overview

  • Product name
    Human RNF70 peptide

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      GQESSKPVWPNPT-C
    • Amino acids
      2 to 14

Specifications

Our Abpromise guarantee covers the use of ab23047 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • E3 ubiquitin-protein ligase Praja 1
    • E3 ubiquitin-protein ligase Praja-1
    • PJA1
    • PJA1_HUMAN
    • PRAJA 1
    • Praja ring finger 1
    • Praja1
    • RING finger protein 70
    • RNF 70
    • RP23-414J22.4
    see all
  • Function
    Has E2-dependent E3 ubiquitin-protein ligase activity. Ubiquitinates MAGED1 antigen leading to its subsequent degradation by proteasome (By similarity). May be involved in protein sorting.
  • Tissue specificity
    Expressed in various regions of the brain including the cerebellum, cerebral cortex, medulla, occipital pole, frontal lobe, temporal lobe and putamen. Highest levels in the cerebral cortex.
  • Sequence similarities
    Contains 1 RING-type zinc finger.
  • Domain
    The RING-type zinc finger domain interacts with an ubiquitin-conjugating enzyme (E2) and facilitates ubiquitination.
  • Post-translational
    modifications
    Substrate for E2-dependent ubiquitination.
  • Information by UniProt

References

ab23047 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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