Human RPL5 protein fragment (ab91956)
- Product nameHuman RPL5 protein fragmentSee all RPL5 proteins and peptides ...
- SourceE. coli
- Amino Acid Sequence
- SequenceYCTGLLLARRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQ PGAFTCYLDAGLA RTTTGNKVFGALKGAVDGGLSIPHS TKRFPGYDSESKEFNAEVHRKHIMGQNV ADYMRYLMEE DEDAYKKQFSQYIKNSVTPDMMEEMYKKAHAAIRENPVYE KKP KKEVKKKRWNRPKMSLAQKKDRVAQKKASFLRAQE RAAES
- Amino acids99 to 297
Our Abpromise guarantee covers the use of ab91956 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- Concentration information loading...
Preparation and Storage
- Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
- ReconstitutionReconstitute with 46 µl distilled water.
- 60S ribosomal protein L5
- Ribosomal protein L5
- RP L5
- RPL 5
- U21 RNA
- FunctionRequired for rRNA maturation and formation of the 60S ribosomal subunits. This protein binds 5S RNA.
- Involvement in diseaseDefects in RPL5 are the cause of Diamond-Blackfan anemia type 6 (DBA6) [MIM:612561]. DBA6 is a form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies.
- Sequence similaritiesBelongs to the ribosomal protein L18P family.
- Cellular localizationCytoplasm. Nucleus > nucleolus.
Human RPL5 protein fragment images
The image shows an electrophoretic assay performed using an Agilent 5100 ALP. In some images coloured control bands can be seen at 15 kDa (green) and/or 240 kDa (purple). The protein-specific band is blue.
References for Human RPL5 protein fragment (ab91956)
ab91956 has not yet been referenced specifically in any publications.