Anti-Human Serum Albumin antibody [1G2] (ab28405)

Overview

  • Product name
    Anti-Human Serum Albumin antibody [1G2]
    See all Human Serum Albumin primary antibodies
  • Description
    Mouse monoclonal [1G2] to Human Serum Albumin
  • Tested applications
    Suitable for: ChIP, ELISA, IP, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length purified human serum albumin protein

  • Positive control
    • Purified human serum albumin protein
  • General notes

    This product was changed from ascites to tissue culture supernatant on 18th September 2017. Lot numbers higher than GR218079 will be from tissue culture supernatant. Please note that the dilutions may need to be adjusted accordingly.

Properties

Applications

Our Abpromise guarantee covers the use of ab28405 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ChIP
ELISA
IP
WB
  • Application notes
    ELISA: Use at an assay dependent dilution.
    IP: Use at a concentration of 1 µg/ml lysate.
    WB: 1/2000. Detects a band of approximately 69 kDa (predicted molecular weight: 69 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
    • Tissue specificity
      Plasma.
    • Involvement in disease
      Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.
    • Sequence similarities
      Belongs to the ALB/AFP/VDB family.
      Contains 3 albumin domains.
    • Post-translational
      modifications
      Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
      Glycated in diabetic patients.
      Phosphorylation sites are present in the extracelllular medium.
      Acetylated on Lys-223 by acetylsalicylic acid.
    • Cellular localization
      Secreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • alb antibody
      • ALBU_HUMAN antibody
      • Albumin (32 AA) antibody
      • Albumin (AA 34) antibody
      • Albumin antibody
      • Analbuminemia antibody
      • Bisalbuminemia antibody
      • Cell growth inhibiting protein 42 antibody
      • DKFZp779N1935 antibody
      • Dysalbuminemic hyperthyroxinemia antibody
      • Growth inhibiting protein 20 antibody
      • HSA antibody
      • Hyperthyroxinemia dysalbuminemic antibody
      • PRO0883 antibody
      • PRO0903 antibody
      • PRO1341 antibody
      • Serum albumin antibody
      see all

    Images

    • All lanes : Anti-Human Serum Albumin antibody [1G2] (ab28405) (1/2000 dilution)

      Lane 1 : Human serum albumin proteins purified from human plasma
      Lane 2 : Human plasma


      Predicted band size : 69 kDa
      Observed band size : 69 kDa

    References

    ab28405 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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