Human SIAH Interacting Protein peptide (ab23014)

Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceC-VESREKQAKGDTEF
    • Amino acids215 to 228

Specifications

Our Abpromise guarantee covers the use of ab23014 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • CacyBP
    • Calcyclin binding protein
    • Calcyclin-binding protein
    • CYBP_HUMAN
    • GIG 5
    • GIG5
    • Growth inhibiting gene 5
    • Growth inhibiting gene 5 protein
    • hCacyBP
    • MGC87971
    • PNAS 107
    • PNAS107
    • RP1 102G20.6
    • S100A6 binding protein
    • S100A6-binding protein
    • S100A6BP
    • Siah-interacting protein
    • SIP
    see all
  • FunctionMay be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).
  • Sequence similaritiesContains 1 CS domain.
    Contains 1 SGS domain.
  • Post-translational
    modifications
    Phosphorylated on serine residues. Phosphorylated upon induction by RA or at high calcium concentrations.
  • Cellular localizationNucleus. Cytoplasm. Cytoplasmic at low calcium concentrations. In neuroblastoma cells, after a retinoic acid (RA) induction and calcium increase, it localizes in both the nucleus and cytoplasm. The nuclear fraction may be phosphorylated.
  • Information by UniProt

References for Human SIAH Interacting Protein peptide (ab23014)

ab23014 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab23014.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"