Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceC-ASKQLGSPTADLA
    • Amino acids1030 to 1042

Associated products

Specifications

Our Abpromise guarantee covers the use of ab23193 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-SIPA1 antibody (ab10162)

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • GTPase activating protein Spa 1
    • GTPase-activating protein Spa-1
    • MGC102688
    • MGC17037
    • p130 SPA-1
    • p130 SPA1
    • Signal induced proliferation associated 1
    • Signal induced proliferation associated gene 1
    • Signal induced proliferation associated protein 1
    • Signal-induced proliferation-associated protein 1
    • SIPA 1
    • Sipa-1
    • Sipa1
    • SIPA1_HUMAN
    • Spa1
    see all
  • FunctionGTPase activator for the nuclear Ras-related regulatory proteins Rap1 and Rap2 in vitro, converting it to the putatively inactive GDP-bound state.
  • Tissue specificityExpressed in fetal as well as in adult tissues. Expressed abundantly in the lymphoid tissues such as thymus, spleen and peripheral blood lymphocytes and also shows a significant expression in the spinal cord.
  • Sequence similaritiesContains 1 PDZ (DHR) domain.
    Contains 1 Rap-GAP domain.
  • Cellular localizationNucleus. Cytoplasm > perinuclear region. Endomembrane system. Mostly localized in the perinuclear membraneous region.
  • Information by UniProt

References for Human SIPA1 peptide (ab23193)

ab23193 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab23193.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"